8-oxo-dGTP diphosphatase (, ''MutT'', ''7,8-dihydro-8-oxoguanine triphosphatase'', ''8-oxo-dGTPase'', ''7,8-dihydro-8-oxo-dGTP pyrophosphohydrolase'') is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivial ...
''8-oxo-dGTP diphosphohydrolase''.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
:
: 8-oxo-dGTP + H
2O
8-oxo-dGMP +
diphosphate
In chemistry, pyrophosphates are phosphorus oxyanions that contain two phosphorus atoms in a P–O–P linkage. A number of pyrophosphate salts exist, such as disodium pyrophosphate (Na2H2P2O7) and tetrasodium pyrophosphate (Na4P2O7), among othe ...
This enzyme requires Mg
2+.
References
External links
*
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EC 3.6.1